21c Museum Hotel St. Louis

Saint Louis, Missouri

8.5 Deluxe

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Choose Your Room

We recommend booking a stay with free cancellation in case your plans change.

S2Q
Guest room, at 21c Museum Hotel St. Louis
Room Image Coming Soon

Guest room

  • Bunk room

USD $ 146 /nt

Limited availability.

BEST FLEXIBLE RATE

You have until December 21, 2024 to cancel this reservation without penalty.

USD $146 /nt
$511 for 3 nights
includes taxes & fees
Price breakdown

D1K
Deluxe room, 1 King bed, at 21c Museum Hotel St. Louis
Room Image Coming Soon

Deluxe room, 1 King bed

  • Deluxe King accessible
  • Accessible room

  • • Full Breakfast for up to two guests
  • • $50 USD Food & Beverage Credit, once per stay
  • • The following amenities are subject to availability at the time of check-in/departure:Early Check-In

You have until December 21, 2024 to cancel this reservation without penalty.

USD $207 /nt
$723 for 3 nights
includes taxes & fees
Price breakdown

BEST FLEXIBLE RATE

You have until December 21, 2024 to cancel this reservation without penalty.

USD $153 /nt
$534 for 3 nights
includes taxes & fees
Price breakdown

A1K
Deluxe room, 1 King bed, at 21c Museum Hotel St. Louis
Room Image Coming Soon

Deluxe room, 1 King bed

  • Deluxe King

  • • Full Breakfast for up to two guests
  • • $50 USD Food & Beverage Credit, once per stay
  • • The following amenities are subject to availability at the time of check-in/departure:Early Check-In

You have until December 21, 2024 to cancel this reservation without penalty.

USD $207 /nt
$723 for 3 nights
includes taxes & fees
Price breakdown

BEST FLEXIBLE RATE

You have until December 21, 2024 to cancel this reservation without penalty.

USD $153 /nt
$534 for 3 nights
includes taxes & fees
Price breakdown

B2Q
Deluxe room, 2 Double or Full beds, 1 Queen bed, at 21c Museum Hotel St. Louis
Room Image Coming Soon

Deluxe room, 2 Double or Full beds, 1 Queen bed

  • Deluxe Double Queen accessible
  • Accessible room

  • • Full Breakfast for up to two guests
  • • $50 USD Food & Beverage Credit, once per stay
  • • The following amenities are subject to availability at the time of check-in/departure:Early Check-In

You have until December 21, 2024 to cancel this reservation without penalty.

USD $216 /nt
$755 for 3 nights
includes taxes & fees
Price breakdown

A2Q
Deluxe room, 2 Double or Full beds, 1 Queen bed, at 21c Museum Hotel St. Louis
Room Image Coming Soon

Deluxe room, 2 Double or Full beds, 1 Queen bed

  • Deluxe Double Queen

  • • Full Breakfast for up to two guests
  • • $50 USD Food & Beverage Credit, once per stay
  • • The following amenities are subject to availability at the time of check-in/departure:Early Check-In

You have until December 21, 2024 to cancel this reservation without penalty.

USD $216 /nt
$755 for 3 nights
includes taxes & fees
Price breakdown

D2Q
Luxury room, 1 Double or Full bed, 1 Queen bed, at 21c Museum Hotel St. Louis
Room Image Coming Soon

Luxury room, 1 Double or Full bed, 1 Queen bed

  • Luxury Double Queen

  • • Full Breakfast for up to two guests
  • • $50 USD Food & Beverage Credit, once per stay
  • • The following amenities are subject to availability at the time of check-in/departure:Early Check-In

You have until December 21, 2024 to cancel this reservation without penalty.

USD $225 /nt
$786 for 3 nights
includes taxes & fees
Price breakdown

E2Q
Deluxe room, 2 Double or Full beds, 1 Queen bed, at 21c Museum Hotel St. Louis
Room Image Coming Soon

Deluxe room, 2 Double or Full beds, 1 Queen bed

  • Deluxe Double Queen roll in shower
  • Accessible room

  • • Full Breakfast for up to two guests
  • • $50 USD Food & Beverage Credit, once per stay
  • • The following amenities are subject to availability at the time of check-in/departure:Early Check-In

You have until December 21, 2024 to cancel this reservation without penalty.

USD $225 /nt
$786 for 3 nights
includes taxes & fees
Price breakdown

B1K
Corner room, 1 King bed, at 21c Museum Hotel St. Louis
Room Image Coming Soon

Corner room, 1 King bed

  • Corner King

USD $ 239 /nt

Limited availability.

BEST FLEXIBLE RATE

You have until December 21, 2024 to cancel this reservation without penalty.

USD $239 /nt
$838 for 3 nights
includes taxes & fees
Price breakdown

P2Q
Loft, 1 Double or Full bed, 1 Queen bed, at 21c Museum Hotel St. Louis
Room Image Coming Soon

Loft, 1 Double or Full bed, 1 Queen bed

  • Loft Double Queen
  • Loft

USD $ 259 /nt

Limited availability.

BEST FLEXIBLE RATE

You have until December 21, 2024 to cancel this reservation without penalty.

USD $259 /nt
$909 for 3 nights
includes taxes & fees
Price breakdown

E1K
Deluxe room, 1 King bed, at 21c Museum Hotel St. Louis
Room Image Coming Soon

Deluxe room, 1 King bed

  • Deluxe King suite accessible roll in shower

USD $ 289 /nt

Limited availability.

BEST FLEXIBLE RATE

You have until December 21, 2024 to cancel this reservation without penalty.

USD $289 /nt
$1,014 for 3 nights
includes taxes & fees
Price breakdown

S1K
Deluxe room, 1 King bed, at 21c Museum Hotel St. Louis
Room Image Coming Soon

Deluxe room, 1 King bed

  • Deluxe King suite

USD $ 289 /nt

Limited availability.

BEST FLEXIBLE RATE

You have until December 21, 2024 to cancel this reservation without penalty.

USD $289 /nt
$1,014 for 3 nights
includes taxes & fees
Price breakdown

J1K
Corner room, 1 King bed, at 21c Museum Hotel St. Louis
Room Image Coming Soon

Corner room, 1 King bed

  • Corner King suite

USD $ 389 /nt

Limited availability.

BEST FLEXIBLE RATE

You have until December 21, 2024 to cancel this reservation without penalty.

USD $389 /nt
$1,365 for 3 nights
includes taxes & fees
Price breakdown

V1K
1 King bed, at 21c Museum Hotel St. Louis
Room Image Coming Soon

1 King bed

  • 21c King suite

USD $ 489 /nt

Limited availability.

BEST FLEXIBLE RATE

You have until December 21, 2024 to cancel this reservation without penalty.

USD $489 /nt
$1,715 for 3 nights
includes taxes & fees
Price breakdown

P1K
1 King bed, at 21c Museum Hotel St. Louis
Room Image Coming Soon

1 King bed

  • Library King suite

USD $ 489 /nt

Limited availability.

BEST FLEXIBLE RATE

You have until December 21, 2024 to cancel this reservation without penalty.

USD $489 /nt
$1,715 for 3 nights
includes taxes & fees
Price breakdown

T1K
Luxury room, 1 King bed, at 21c Museum Hotel St. Louis
Room Image Coming Soon

Luxury room, 1 King bed

  • Luxury King suite

USD $ 489 /nt

Limited availability.

BEST FLEXIBLE RATE

You have until December 21, 2024 to cancel this reservation without penalty.

USD $489 /nt
$1,715 for 3 nights
includes taxes & fees
Price breakdown

Please note, room photos and descriptions are representative of the room category. Actual rooms may vary from what is shown. Upgrades, early check-in, and late check-out are based on availability.

About the Hotel

21c Museum Hotels reimagines a historic St. Louis fixture: the 10-story, Renaissance Revival-style YMCA building. Located in the heart of downtown St. Louis, and a short walk from the City Museum and CITYPARK stadium, 21c Museum Hotel St. Louis includes a 173-room boutique hotel, contemporary art museum, Idol Wolf restaurant, Good Press café, and Locust Street Athletic and Swim Club, a full-service wellness center. With more than 14,000 square feet of exhibition and meeting & event space seamlessly integrated into all areas of the property, there are opportunities to discover contemporary art around every corner.

Location

21c Museum Hotel St. Louis
1528 Locust Street
Saint Louis, Missouri 63103

Nearest Airport: STL

Features and Amenities

  • General Information
  • Pet Friendly
  • Dining
  • Cafe
  • Bar & Lounge
  • On-Site Amenities
  • Pool
  • Spa Services
  • Laundry Service
  • Fitness Center
  • WiFi
  • 24-Hour Front Desk
  • In-Room Amenities
  • Air Conditioning
  • Hair Dryers
  • Flat-Screen Televisions
  • Coffee & Tea Facilities
  • Blackout Curtains
  • Business
  • Business Center/Services
  • Nearby
  • Museums
  • Interests
  • Hotels
  • Signature Perks

Reviews for 21c Museum Hotel St. Louis

The bellman was amazing! Highlight of my stay.

TripAdvisor Traveler Review Rating Reviewed 6 days ago

Kevin and Colin made my trip amazing. It was only me and my two children they made sure we were safe. However in my room the telephone did not work. The bellman was amazing! Highlight of my stay. I also enjoyed the complementary beverage nice way to wind down with children

Leonka C


Thanks Kevin at Valet!

TripAdvisor Traveler Review Rating Reviewed 2 weeks ago

We had an event there and Kevin at valet was incredible! He helped us unload our cars and take them to the event space. He went out of his way to make sure we had everything we needed and were set up in the space before he left. Thanks Kevin Huge shoutout!!

Aly H


Classy hotel close to the stunning Fox Theatre.

TripAdvisor Traveler Review Rating Reviewed 1 month ago

An elegant hotel with a lovely pool and fitness center. I spent four nights there and received outstanding service. The rooms were inviting, and the bed was comfortable. The bar was beautiful, and the art gallery is so cool. I will definitely be back.

Raquel M


Terrible. Bad stuff, bad room, bad neighborhood.

TripAdvisor Traveler Review Rating Reviewed 1 month ago

Terrible. We booked the “corner king.” From the photos on the website, it had a “sitting” area with a couch. Nope. Got to the room, and it’s a table with one chair and a stool. Seriously. Called down to complain, and were told that some of the “corner kings” have this configuration. BULL. Typical bait and switch. Also, the blower on the HVAC is so loud you really won’t believe it. We couldn’t hear the tv over it. The neighborhood is sketchy, so don’t plan to do a lot of walking around. Stay anywhere but here. Can’t believe this is a 21C property. What a joke!

veritas71 - Memphis, Tennessee


Kevin is great!

TripAdvisor Traveler Review Rating Reviewed 1 month ago

Kevin at the valet was so kind and helpful! He provided such wonderful assistance. He also made sure to tell us about the art gallery in the restaurant so we wouldn’t miss out on it. Would definitely recommend coming to both the restaurant and museum.

Ericka T


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