21c Museum Hotel St. Louis

Saint Louis, Missouri

8.4 Moderate Deluxe

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Choose Your Room

We recommend booking a stay with free cancellation in case your plans change.

S2Q
Guest room, at 21c Museum Hotel St. Louis
Room Image Coming Soon

Guest room

  • Bunk room

USD $ 210 /nt

Limited availability.

BEST FLEXIBLE RATE

You have until April 24, 2025 to cancel this reservation without penalty.

USD $210 /nt
$734 for 3 nights
includes taxes & fees
Price breakdown

A1K
Deluxe room, 1 King bed, at 21c Museum Hotel St. Louis
Room Image Coming Soon

Deluxe room, 1 King bed

  • Deluxe King

  • • Full Breakfast for up to two guests
  • • $50 USD Food & Beverage Credit, once per stay
  • • The following amenities are subject to availability at the time of check-in/departure:Early Check-In

You have until April 30, 2025 to cancel this reservation without penalty.

USD $219 /nt
$765 for 3 nights
includes taxes & fees
Price breakdown

D2Q
Luxury room, 1 Double or Full bed, 1 Queen bed, at 21c Museum Hotel St. Louis
Room Image Coming Soon

Luxury room, 1 Double or Full bed, 1 Queen bed

  • Luxury Double Queen

  • • Full Breakfast for up to two guests
  • • $50 USD Food & Beverage Credit, once per stay
  • • The following amenities are subject to availability at the time of check-in/departure:Early Check-In

You have until April 30, 2025 to cancel this reservation without penalty.

USD $318 /nt
$1,112 for 3 nights
includes taxes & fees
Price breakdown

E2Q
Deluxe room, 2 Double or Full beds, 1 Queen bed, at 21c Museum Hotel St. Louis
Room Image Coming Soon

Deluxe room, 2 Double or Full beds, 1 Queen bed

  • Deluxe Double Queen roll in shower
  • Accessible room

  • • Full Breakfast for up to two guests
  • • $50 USD Food & Beverage Credit, once per stay
  • • The following amenities are subject to availability at the time of check-in/departure:Early Check-In

You have until April 30, 2025 to cancel this reservation without penalty.

USD $318 /nt
$1,112 for 3 nights
includes taxes & fees
Price breakdown

P2Q
Loft, 1 Double or Full bed, 1 Queen bed, at 21c Museum Hotel St. Louis
Room Image Coming Soon

Loft, 1 Double or Full bed, 1 Queen bed

  • Loft Double Queen
  • Loft

USD $ 327 /nt

Limited availability.

BEST FLEXIBLE RATE

You have until April 24, 2025 to cancel this reservation without penalty.

USD $327 /nt
$1,144 for 3 nights
includes taxes & fees
Price breakdown

Please note, room photos and descriptions are representative of the room category. Actual rooms may vary from what is shown. Upgrades, early check-in, and late check-out are based on availability.

About the Hotel

21c Museum Hotels reimagines a historic St. Louis fixture: the 10-story, Renaissance Revival-style YMCA building. Located in the heart of downtown St. Louis, and a short walk from the City Museum and CITYPARK stadium, 21c Museum Hotel St. Louis includes a 173-room boutique hotel, contemporary art museum, Idol Wolf restaurant, Good Press café, and Locust Street Athletic and Swim Club, a full-service wellness center. With more than 14,000 square feet of exhibition and meeting & event space seamlessly integrated into all areas of the property, there are opportunities to discover contemporary art around every corner.

Location

21c Museum Hotel St. Louis
1528 Locust Street
Saint Louis, Missouri 63103

Nearest Airport: STL

Features and Amenities

  • General Information
  • Pet Friendly
  • Dining
  • Cafe
  • Bar & Lounge
  • On-Site Amenities
  • Pool
  • Spa Services
  • Laundry Service
  • Fitness Center
  • WiFi
  • 24-Hour Front Desk
  • In-Room Amenities
  • Air Conditioning
  • Hair Dryers
  • Flat-Screen Televisions
  • Coffee & Tea Facilities
  • Blackout Curtains
  • Business
  • Business Center/Services
  • Nearby
  • Museums
  • Interests
  • Hotels
  • Signature Perks

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